2011.09 - 2015.06?? 華南理工大學(xué)???? 生物工程???????? 學(xué)士
2015.09 - 2020.07?? 中國(guó)科學(xué)院大學(xué)?? 發(fā)育生物學(xué)?????? 博士
2020.07 - 2022.10?? 中科院廣州生物醫(yī)藥與健康研究院??? 博士后
2022.11 - 2022.12?? 中科院廣州生物醫(yī)藥與健康研究院??? 助理研究員
2023.01 - 至今???? 中科院廣州生物醫(yī)藥與健康研究院??? 副研究員
l?精準(zhǔn)基因編輯技術(shù)開(kāi)發(fā)及應(yīng)用
l?人類遺傳疾病基因治療
l?早衰癥機(jī)理及治療研究
l?心臟發(fā)育與再生生物學(xué)
l?國(guó)家自然科學(xué)基金青年項(xiàng)目（1項(xiàng)，主持）
l?中國(guó)博士后科學(xué)基金面上項(xiàng)目（1項(xiàng)，主持）
l?海南省科技計(jì)劃（三亞崖州灣科技城自然科學(xué)基金聯(lián)合項(xiàng)目，1項(xiàng)，主持）
l?廣州市科技計(jì)劃項(xiàng)目（基礎(chǔ)與應(yīng)用基礎(chǔ)研究項(xiàng)目，1項(xiàng)，主持）
l?GIBH優(yōu)秀研究生獎(jiǎng)學(xué)金
l?廣東省遺傳學(xué)會(huì)第十屆會(huì)員代表大會(huì)暨學(xué)術(shù)研討會(huì)優(yōu)秀論文
1. Xie J*, Ge W*, Li N*, Liu Q*, Chen F, Yang X, Huang X, Ouyang Z, Zhang Q, Zhao Y, Liu Z, Gou S, Wu H, Lai C, Fan N, Jin Q, Shi H, Liang Y, Lan T, Quan L, Li X, Wang K, Lai L. Efficient base editing for multiple genes and loci in pigs using base editors[J]. Nature Communication, 2019, 10(1):2852.
2. Liang, Y.*, Xie, J.*, Zhang, Q.*, Wang, X.*, Gou, S., Lin, L., Chen, T., Ge, W., Zhuang, Z., Lian, M., Chen, F., Li, N., Ouyang, Z., Lai, C., Liu, X., Li, L., Ye, Y., Wu, H., Wang, K., & Lai, L. (2022). AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns. Nucleic acids research, 50(9), 5384–5399.
3. Xie, J.*, Huang, X.*, Wang, X., Gou, S., Liang, Y., Chen, F., Li, N., Ouyang, Z., Zhang, Q., Ge, W., Jin, Q., Shi, H., Zhuang, Z., Zhao, X., Lian, M., Wang, J., Ye, Y., Quan, L., Wu, H., Wang, K., Lai, L. (2020). ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems. BMC biology, 18(1), 131.
4. Li, N.*, Gou, S.*, Wang, J.*, Zhang, Q., Huang, X., Xie, J., Li, L., Jin, Q., Ouyang, Z., Chen, F., Ge, W., Shi, H., Liang, Y., Zhuang, Z., Zhao, X., Lian, M., Ye, Y., Quan, L., Wu, H., Lai, L., Wang, K. (2021). CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I. Molecular therapy : the journal of the American Society of Gene Therapy, 29(3), 1001–1015.
5. Wu H, Liu Q, Shi H, Xie J, Zhang Q, Ouyang Z, Li N, Yang Y, Liu Z, Zhao Y, Lai C, Ruan D, Peng J, Ge W, Chen F, Fan N, Jin Q, Liang Y, Lan T, Yang X, Wang X, Lei Z, Doevendans PA, Sluijter JPG, Wang K, Li X, Lai L. Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems[J]. Cell Molecular Life Science, 2018, 75(19):3593-3607.
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專利：
1. 賴良學(xué)；王可品；葛維凱；劉琪帥；謝精科；一種重度免疫缺陷豬模型及其構(gòu)建方法和應(yīng)用，2019-2-25，中國(guó)，CN201910137229.2
2. 賴良學(xué)；王可品；梁艷慧；謝精科；一種融合蛋白及含有其的由雙脫氨酶介導(dǎo)的堿基編輯系統(tǒng)和應(yīng)用，2022-03-01，中國(guó)，CN202210193759.0
